UltraBiotic Akkermansia Plus

Take one capsule daily or as directed by your healthcare practitioner. If you are pregnant, nursing, or taking medication, consult your healthcare practitioner before use. Keep out of reach of children.

Akkermansia muciniphila AH39 supports the mucus layer and gut-barrier integrity and is being explored as a next-generation probiotic; emerging studies characterize AH39’s immunomodulatory activity and Akkermansia’s broader roles in metabolic and mucosal health.

Bifidobacterium animalis subsp. lactis HN019 is documented in randomized trials to improve colonic transit and bowel habit comfort in adults with functional constipation.

Bifidobacterium animalis subsp. lactis B420 has human data suggesting support for weight-management-related endpoints and gut-barrier and metabolic markers.

Lactobacillus rhamnosus GG is one of the most studied probiotics; evidence supports benefits for epithelial barrier function and balanced mucosal immune activity.

Clostridium butyricum is a butyrate-producing symbiont that supports colonocyte energy needs and gut-barrier function, with growing clinical and mechanistic evidence, including recent trials in functional GI conditions.

Serving size 1 capsule
Servings per container 30

Amount per serving
Bifidobacterium animalis HN019 10 billion CFU †
Bifidobacterium animalis B420 10 billion CFU †
Lactobacillus rhamnosus GG 2 billion CFU †
Akkermansia muciniphila AH39 100 million CFU †
Clostridium butyricum 30 million CFU †

Other ingredients
digestive-resistant capsule hypromellose, gellan gum, microcrystalline cellulose, vegetable magnesium stearate, silica
† At time of manufacture.

van Syoc, E. P., Damani, J., DiMattia, Z., et al. 2024. Supplementation with Bifidobacterium lactis HN019 and functional constipation randomized clinical trial. JAMA Network Open.

Stenman, L. K., Lehtinen, M. J., Meland, N., et al. 2016. Probiotic with or without fiber in weight management in overweight adults randomized controlled trial. EBioMedicine.

Lammers, K. M., Brigidi, P., Vitali, B., et al. 2018. Lactobacillus rhamnosus GG-derived mediators support epithelial barrier function. Frontiers in Immunology.

Zhao, Q., et al. 2018. Lactobacillus rhamnosus GG prevents epithelial barrier dysfunction mechanisms of p40. Gut Microbes.

Song, D., et al. 2021. Butyrate-producing human gut symbiont Clostridium butyricum and its probiotic potential review. Gut Microbes.

Huang, C., et al. 2024. Clostridium butyricum in IBS-D clinical outcomes and mechanisms review and trial data. Microorganisms.

Zhang, X., et al. 2023. Species- or genus-dependent immunostimulatory effects of gut-derived bacteria includes characterization of Akkermansia muciniphila AH39. Journal of Advanced Research.